Visweswar Sirish Parupudi

About Me

Hiya, I'm Sirish Visweswar 👋, a machine-learning researcher and engineer with an M.S. in Computer Science from NYU. I'm a Research Engineer at the Neuroinformatics Lab with Prof. Erdem Varol, where I build self-supervised models for large-scale neural and imaging data.

My recent work has two threads. The first is localizing electrodes in the brain directly from the signals they record: geometry-aware self-supervised foundation models on raw Neuropixels LFP, published this year as two NeurIPS 2026 papers (a main-track paper and the LFP2Gene workshop paper). The second is high-speed voltage imaging on a 440 Hz two-photon microscope, in collaboration with Prof. Shy Shoham: I built its image reconstruction for the OJAMI paper (under review at Nature Methods), and a self-supervised denoiser that recovers individual action potentials from shot noise without ever seeing clean ground truth.

My interests sit at the intersection of deep learning, computer vision, and neuroscience, but I've also dabbled in reinforcement learning, game development, full-stack apps, blockchain, and NLP. In the long run, I'm looking to pursue a PhD or research-focused machine learning engineering roles in industry.

Outside of tech, I'm into creating art, which keeps me grounded and feeds into my problem-solving style: a mix of creativity, structure, and curiosity.

Updates

[Sep 2026] Two papers at NeurIPS 2026! "Geometry-Aware Self-Supervised Electrophysiology Representation Learning" in the main track and "LFP2Gene" at the BrainBodyFM workshop, both as co-first author. [Papers]

[May 2026] Completed my M.S. in Computer Science at NYU (GPA 3.85); continuing full-time as a Research Engineer at the NYU Neuroinformatics Lab.

[Jan 2026] Started as a Graduate Assistant for Neuroinformatics.

[Sep 2025] Started as a Graduate Assistant for Computer Vision.

[Jun 2025] Joined the NYU Neuroinformatics Lab with Prof. Erdem Varol.

[Sep 2024] Started my M.S. in Computer Science at NYU Tandon School of Engineering.

[Aug 2024] Graduated from BITS Pilani, Hyderabad with a B.E. in Electronics and Communication Engineering.

[Nov 2023] Published in IEEE Sensors Letters on smartphone deep learning for heart-attack detection from ECG.

[Jun 2023] Started my undergraduate thesis internship at the Speech & Language Lab, NTU Singapore.

Resume

Resume of Visweswar Sirish Parupudi

Publications

Figure 1: pipeline from Neuropixels LFP chunks through audio foundation model backbones and geometry-aware contrastive objectives to 3D coordinate regression

Localizing recording electrodes in 3D directly from raw single-channel LFP, without histology, using probe geometry as a self-supervisory signal.

Figure 1 of LFP2Gene: frozen wav2vec 2.0 LFP encoder with a decoder predicting Allen MERFISH gene expression around each channel

LFP2Gene: Recovering Local Molecular Composition from Local Field Potentials | NeurIPS 2026 BrainBodyFM Workshop · Co-first author

Self-supervised LFP representations retain signatures of the local molecular environment around the electrode.

Denoised two-photon voltage imaging frame recorded with OJAMI

OJAMI: Electro-Optic Jitter Accelerated Multiphoton Imaging | Nature Methods (under review) · Co-author

An add-on electro-optic scan module giving standard two-photon microscopes an order-of-magnitude speed-up at subcellular resolution.

ECG Classification Publication

Ensemble deep learning model for real-time myocardial infarction detection on mobile devices using ECG traces.

Projects

CineMatch Movie Platform

Django + React movie discovery platform with personalized recommendations, community genre rooms, and real-time chat.

Med-GEMMA X-Ray Pipeline

Production-grade pipeline for automated radiology report generation with Kafka, Spark, and S3 data lake.

Scrabble RL Project

Custom OpenAI Gym-compliant Scrabble environment with multiple RL agents and comprehensive benchmarking.

PinToBeans Social Platform

PinToBeans

Full-stack social media platform with real-time features, content sharing, and comprehensive user engagement tools.

EEG Classification Project

Deep learning pipeline using Multi-View Transformer for neurological condition classification from 19-channel EEG data.

Det-IGEN Watermarking Project

Invisible tree ring watermarking system for Diffusion Models to detect AI-generated content.

Noisy tweet with tagged entities, paraphrased by LLaMA 2 and filtered by BERTScore

Entity-preserving text augmentation and LLM paraphrasing for named-entity recognition on noisy social-media language.

Hate Speech Detection Project

Multi-class hate speech detection system using 11 Twitter datasets with advanced NLP techniques.

Gaming Assets NFT Marketplace

Specialized gaming NFT marketplace on Polygon network for trading in-game assets as ERC-721 tokens.

LED Audio Visualizer Project

Audio spectrum visualizer with LED matrix that responds to music in real-time.

Games

Games developed as part of game design coursework and personal projects.

View Complete Game Portfolio
Zombieland Game

Survival horror game featuring zombie apocalypse scenarios with strategic gameplay elements.

Outpost Epsilon Game

Space exploration game set in a remote outpost with mystery and adventure elements.

Zero Vector Game

Gravity-shifting boss fight platformer game featuring dynamic physics-based gameplay mechanics.

Penguin Adventure Game

Charming adventure game featuring a penguin protagonist in arctic environments with puzzle elements.

Teaching

Graduate Courses (NYU)

100+ graduate students across both courses · 8 Kaggle competitions curated

CS-GY 6643: Computer Vision

Graduate Assistant · Fall 2025

Graduate course from classical image processing to modern deep learning for vision.

CS-GY 9223: Neuroinformatics

Graduate Assistant · Spring 2026

Graduate course at the intersection of neuroscience, machine learning, and large-scale neural data.

Teaching Resources

Materials I built for the courses

Guest Lectures & Workshops

Mentored workshop guiding students through Arduino-based line follower bot development, covering sensor integration, motor control, and algorithm implementation.

60+ students Arduino projects

Techtainment Robotics Project

BITS Pilani 2022-2023

Guided a team of 5 students in developing an innovative robotics headgear project, providing mentorship in hardware integration, programming, and project management.

5 team members Headgear robotics